About this Talk
A comprehensive exploration of how Chronic Inflammatory Response Syndrome (CIRS) impacts testosterone levels, particularly through inflammatory pathways and metabolic disruption.
Key Takeaways:
Understanding Natural Testosterone Decline
- Peaks around age 20
- Declines by ~30% by age 30
- ~50% loss by age 50
- Accelerated decline possible with comorbidities
CIRS Impact on Hormones
- Affects ~25% of population genetically
- Can lower testosterone in 40-50% of cases
- Creates inflammatory cascade affecting multiple hormones
- Often missed in conventional testing
- Commonly triggered by water-damaged buildings
Warning Signs & Symptoms
- Decreased libido and morning erections
- Mental fatigue and concentration issues
- Unexplained weight gain
- Sleep disturbances
- Mood changes
- Physical stamina decrease
- Hot flushes/sweating attacks
The Inflammation-Obesity-Testosterone Connection
- Obesity can reduce testosterone by 50%
- Creates vicious cycle of inflammation
- Leptin resistance common feature
- Can lead to increased oestrogen conversion
Treatment Considerations
- Address underlying inflammation first
- Consider CIRS protocol if indicated
- Test for aromatase activity before TRT
- Monitor both free and total testosterone
- Address environmental triggers
Critical Points:
- Only 12-35% of testosterone-deficient men receive treatment
- Simple testosterone replacement may not help if CIRS present
- Environmental factors often overlooked
- Need comprehensive approach including inflammation control
Action Steps:
- Test comprehensively before treatment
- Address environmental exposures
- Consider inflammatory markers
- Work with CIRS-literate practitioner
- Address metabolic health simultaneously
- Monitor aromatase activity
- Focus on root causes rather than symptoms
This presentation emphasises the importance of addressing underlying inflammatory conditions before or alongside testosterone optimization efforts.
The information, content, and materials presented during here are for informational and educational purposes only. They do not constitute medical advice, diagnosis, or treatment, and should not be considered a substitute for professional medical consultation, diagnosis, or treatment.