Amy Pearlman

The Tale Of The Middle Aged Male

A Talk by Amy Pearlman (Prime Institute)

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About this Talk

Dr. Pearlman shares insights from her clinical practice, challenging conventional views about testosterone deficiency and highlighting the broader impact of hormones on male health beyond sexual function.

Key Takeaways:

Demographics & Decline

  • Testosterone issues affecting men as early as 30s-40s
  • Natural decline of ~1% per year after age 30
  • Age alone doesn't predict testosterone levels
  • Young men increasingly experiencing issues earlier than expected

Beyond Sexual Health

  • Testosterone is more than a "sex hormone"
  • Impacts brain function, energy, and overall vitality
  • Affects multiple body systems
  • Brain fog and cognitive issues are common complaints

Common Presenting Symptoms

  • Reduced motivation and energy
  • Difficulty with weight management
  • Decreased muscle mass despite exercise
  • Cognitive challenges ("brain fog")
  • Mood changes and anxiety
  • Sexual health concerns

Clinical Assessment

  • Standard questionnaires have limitations
  • Blood tests essential for diagnosis
  • Individual symptoms vary significantly
  • Treatment success measured by personal goals

Case Studies Highlighted

  • 47-year-old: Weight loss success with combined approach
  • 62-year-old lawyer: Cognitive improvement primary benefit
  • 65-year-old: Enhanced response to ED medication

Important Considerations:

  • Low testosterone testing should be comprehensive
  • Treatment can be safely discontinued if ineffective
  • Results often visible in multiple areas of life
  • Individual response and goals vary significantly

Treatment Philosophy:

  • Focus on patient's primary concerns
  • Track measurable metrics beyond weight
  • Combine hormone optimisation with lifestyle changes
  • Consider whole-body impact, not just sexual function


The information, content, and materials presented during here are for informational and educational purposes only. They do not constitute medical advice, diagnosis, or treatment, and should not be considered a substitute for professional medical consultation, diagnosis, or treatment.

About The Speaker

Amy Pearlman

Amy Pearlman

Prime Institute

Board certified-urologist and expert on male hormonal health

Chroma

Lights Designed For Humans

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